Scientific KnowledgeAnimal study (in vivo)Mouse
SG
Sharon G. Kujawa
Eaton-Peabody Laboratories / Harvard Medical School
Cochlear synaptopathy and primary neural degeneration after noise exposure and aging.
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Laboratory1
Hypotheses1
Papers (2)
Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009
The seminal finding: a 'temporary' noise-induced threshold shift that fully recovers still leaves permanent, silent damage, acute loss of nerve terminals and delayed degeneration of the cochlear nerve.
Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms.
Hearing research · 2017
Review: well before hair cells die and thresholds rise, noise and aging silently sever the synapses between inner hair cells and the auditory nerve.
ReviewN/A