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Karen Avraham
Professor of Human Molecular Genetics, Tel Aviv University
Genetics of hereditary deafness and single-cell mapping of regenerative potential in the cochlea.
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Laboratory1
Papers (2)
Live imaging and multimodal profiling reveal transdifferentiation of a cochlear supporting cell subpopulation upon Notch inhibition.
Science advances · 2026
Single-cell profiling of the neonatal mouse cochlea finds that only a rare subpopulation of supporting cells actually retains the ability to become hair cells when Notch is inhibited.
Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness.
EMBO molecular medicine · 2021
Uses AAV gene therapy to correct SYNE4, a deafness gene Avraham's lab helped characterize, achieving near-complete hearing rescue in newborn mice.