Anna R. Chambers

Eaton-Peabody Laboratories

Central gain and compensatory plasticity after near-complete cochlear denervation.

Hypotheses

Treatments

Laboratory

Papers

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Laboratory1

Eaton-Peabody Laboratories

Hypotheses2

PV Interneuron Dysfunction Central Gain

Papers (1)

Central Gain Restores Auditory Processing following Near-Complete Cochlear Denervation.

Neuron · 2016

After near-complete cochlear denervation, the cortex ramps up 'central gain' to restore basic sound detection, compensation that can overshoot into hyperactivity.

Animal study (in vivo)Mouse