When Silence
Scientific Knowledge
ZT

Zheng-Quan Tang

Professor, School of Life Sciences and Medical Engineering, Anhui University

How neuromodulators, especially serotonin, control central auditory circuit activity and drive pathological auditory processing including tinnitus.

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Papers (1)

A discrete serotonergic circuit involved in the generation of tinnitus behavior.

Proceedings of the National Academy of Sciences of the United States of America · 2026

A serotonergic dorsal raphe → dorsal cochlear nucleus circuit drives fusiform-cell hyperactivity and tinnitus-like behavior in mice, reversible by blocking 5-HT2A receptors.

Animal study (in vivo)
Mouse