Scientific KnowledgeAnimal study (in vivo)MouseAnimal study (in vivo)Mouse
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Laurence O. Trussell
Vollum Institute, Oregon Health & Science University
Synaptic physiology of auditory brainstem circuits.
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Hypotheses1
Papers (2)
Descending Axonal Projections from the Inferior Colliculus Target Nearly All Excitatory and Inhibitory Cell Types of the Dorsal Cochlear Nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
The inferior colliculus doesn't just receive from the DCN, it sends dense feedback projections back, targeting nearly every excitatory and inhibitory cell type there.
A discrete serotonergic circuit involved in the generation of tinnitus behavior.
Proceedings of the National Academy of Sciences of the United States of America · 2026
A serotonergic dorsal raphe → dorsal cochlear nucleus circuit drives fusiform-cell hyperactivity and tinnitus-like behavior in mice, reversible by blocking 5-HT2A receptors.