When Silence
Scientific Knowledge
DD

Dirk De Ridder

Section of Neurosurgery, University of Otago

Tinnitus as an emergent network phenomenon; thalamocortical dysrhythmia and Bayesian models of phantom perception.

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Papers (4)

An integrative model of auditory phantom perception: tinnitus as a unified percept of interacting separable subnetworks.

Neuroscience and biobehavioral reviews · 2014

The flagship model: tinnitus is not one damaged locus but an emergent percept of multiple parallel brain subnetworks, communicating at shared hubs at distinct oscillatory frequencies.

ModelN/A

Thalamocortical Dysrhythmia: A Theoretical Update in Tinnitus.

Frontiers in neurology · 2015

Theoretical update on thalamocortical dysrhythmia: after input loss the thalamus, cortex loop slows from alpha to theta with surrounding gamma, and that theta, gamma coupling carries the phantom sound into consciousness.

ReviewN/A

Thalamocortical dysrhythmia detected by machine learning.

Nature communications · 2018

Human evidence: machine learning on resting EEG detected a thalamocortical dysrhythmia signature that is spectrally equivalent but spatially distinct across tinnitus, pain, Parkinson's and depression.

Human study (non-randomized / first-in-human)
Human

Phantom percepts: tinnitus and pain as persisting aversive memory networks.

Proceedings of the National Academy of Sciences of the United States of America · 2011

Theoretical model proposing tinnitus and chronic pain are persisting 'aversive memory' networks, engaging parahippocampal/memory circuitry alongside the sensory pathway.

ModelN/A